Microglia

Endogenous pleiotrophin and midkine regulate LPS-induced glial responses
Pleiotrophin (PTN) and Midkine (MK) are two growth factors that modulate neuroinflammation. They are overexpressed with certain diseases. Animal models expressing or not these molecules are exposed to different concentrations of a pro-inflammatory substance (LPS).
Rosalía Fernández-Calle, Marta Vicente-Rodríguez, Esther Gramage, Carlos de la Torre, Carmen Pérez-García, María P. Ramos, Gonzalo Herradón
Cite DOI
Endogenous pleiotrophin and midkine regulate LPS-induced glial responses